The efficient repair of double-stranded DNA breaks (DSBs) is essential for genome integrity and cell survival. Homologous recombination is one pathway that is used to repair DSBs, particularly in ...

Homologous recombination involves the precise exchange of similar or identical nucleic acid sequences between two DNA molecules. This process directs the repair of many DNA lesions in somatic cells ...

Red arrows indicate the DNA repair pathways that are known to aid bacterial survival as persisters and gamblers in the presence of fluoroquinolones. Blue color arrow indicates downregulation, while ...

The DNA mismatch repair (MMR) system is a highly conserved post replicative editing process that prevents mutations (for a review see Kolodner, 1996; Modrich and Lahue, 1996). Germline mutations in ...