Duchenne (DMD) and Becker (BMD) muscular dystrophies are allelic neuromuscular disorders which are caused by defects of the dystrophin gene, one third of which arising from new mutations. This 2.5-Mb ...

The illustration of protein structure (domains) on the left side, and corresponding exons in the FLT3 gene are displayed on the right side. FMS-like tyrosine kinase 3 (FLT3) mutations represent some ...

The model suggests that negative KRAS findings are believable when the maximum of APC and TP53 frequencies is at least 8% (corresponding posterior probability of false negative <5%). Validation ...

Inherited mutations in DNA-repair genes are unexpectedly common in men with metastatic prostate cancer and could help guide therapy and inform family member cancer risk SEATTLE - July 6, 2016 - ...

To ensure it complies with the CE marking, the DNA is first isolated from a specimen of formalin-fixed paraffin-embedded tissue using the QIAamp DNA FFPE Tissue Kit. The total amount of DNA in the ...

Novel blood testing technology that combines genome-wide sequencing of single molecules of DNA shed from tumors and machine learning may allow earlier detection of lung and other cancers. Novel blood ...

Researchers have shown that commercially available rapid antigen tests can detect past and present variants of concern and have identified potential mutations that may impact test performance in the ...

A new report shows better than 80% concordance between liquid biopsy and tissue biopsy. Liquid biopsy and analysis of circulating tumor DNA (ctDNA) is a viable option for determining the presence of ...

What Is the MTHFR Gene Mutation? The MTHFR gene mutation is a variation in the MTHFR gene. This gene normally tells your body how to make the MTHFR protein. You need this protein to process folate, ...